Naoaki Saito Selected Research

1-hexylindolactam-V10

1/2008

Synthesis, conformational analysis, and biological evaluation of 1-hexylindolactam-V10 as a selective activator for novel protein kinase C isozymes.

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Naoaki Saito Research Topics

Disease

14	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2019 - 08/2005
11	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 12/2007
8	Neoplasms (Cancer) 12/2018 - 02/2002
4	Alzheimer Disease (Alzheimer's Disease) 08/2022 - 01/2008
3	Hearing Loss (Hearing Impairment) 01/2021 - 01/2018
3	Inflammation (Inflammations) 11/2014 - 09/2008
3	Pain (Aches) 02/2012 - 08/2008
2	Hypoxia (Hypoxemia) 03/2021 - 06/2020
2	Sensorineural Hearing Loss 01/2021 - 01/2018
2	Noise-Induced Hearing Loss (Acoustic Trauma) 01/2021 - 01/2018
2	Hypertrophy 09/2015 - 08/2014
2	Parkinsonian Disorders (Parkinsonism) 07/2014 - 11/2002
2	Neuroblastoma 02/2012 - 09/2007
2	Hepatocellular Carcinoma (Hepatoma) 09/2010 - 04/2009
1	Learning Disabilities (Learning Disability) 08/2022
1	Atrophy 01/2019
1	Parkinson Disease (Parkinson's Disease) 10/2018
1	Xeroderma Pigmentosum (Kaposi's Disease) 03/2017
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2017
1	Adenoma (Adenomas) 09/2015
1	Leukemia 03/2014
1	Starvation 02/2012
1	Dental Caries (Decay, Dental) 05/2011
1	Huntington Disease (Huntington's Disease) 10/2010
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 10/2010
1	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2009
1	Hypersensitivity (Allergy) 12/2009
1	Atopic Dermatitis (Atopic Eczema) 12/2009
1	Skin Diseases (Skin Disease) 12/2009
1	Acquired Immunodeficiency Syndrome (AIDS) 06/2009
1	HIV Infections (HIV Infection) 06/2009
1	Bipolar Disorder (Manic Depressive Psychosis) 12/2008
1	Hyperalgesia 09/2008
1	Congenital Abnormalities (Deformity) 04/2008
1	Reperfusion Injury 01/2008

Drug/Important Bio-Agent (IBA)

10	Protein Kinases (Protein Kinase)IBA 10/2018 - 07/2008
7	Protein Kinase CIBA 04/2017 - 06/2003
7	Mutant Proteins (Protein, Mutant)IBA 01/2014 - 08/2005
7	Phosphotransferases (Kinase)IBA 01/2014 - 08/2005
4	Proteins (Proteins, Gene)FDA Link 06/2020 - 05/2010
4	protein kinase C gamma (PRKCG)IBA 01/2019 - 11/2002
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 09/2008
3	Amyloid (Amyloid Fibrils)IBA 01/2018 - 01/2010
3	Phorbol EstersIBA 01/2014 - 05/2003
3	IsoenzymesIBA 12/2008 - 02/2002
2	AntioxidantsIBA 03/2021 - 01/2018
2	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2021 - 09/2008
2	Nonsense Codon (Nonsense Mutation)IBA 01/2019 - 07/2014
2	Peptides (Polypeptides)IBA 01/2019 - 02/2002
2	Pharmaceutical PreparationsIBA 01/2018 - 12/2002
2	aplysiatoxinIBA 04/2017 - 06/2009
2	Ginkgo biloba extract (Rokan)IBA 09/2015 - 08/2014
2	FlavonoidsIBA 09/2010 - 04/2009
2	bryostatin 1IBA 06/2009 - 02/2002
2	CarcinogensIBA 06/2009 - 02/2002
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 08/2022
1	Acetylcholine (Acetylcholine Chloride)FDA Link 08/2022
1	Donepezil (Aricept)FDA LinkGeneric 08/2022
1	Ketoglutaric Acids (Ketoglutaric Acid)IBA 03/2021
1	Superoxides (Superoxide)IBA 01/2021
1	Cisplatin (Platino)FDA LinkGeneric 01/2021
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2018
1	Hydroxyl RadicalIBA 04/2017
1	Histones (Histone)IBA 03/2017
1	Diacylglycerol KinaseIBA 01/2017
1	DiglyceridesIBA 01/2017
1	Vitamin E FDA LinkGeneric 01/2017
1	Constitutive Androstane ReceptorIBA 09/2015
1	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 09/2015
1	Amyloidogenic ProteinsIBA 01/2015
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2015
1	Heparin (Liquaemin)FDA LinkGeneric 11/2014
1	Dinoprostone (PGE2)FDA Link 11/2014
1	Dopamine (Intropin)FDA LinkGeneric 07/2014
1	AntigensIBA 03/2014
1	EnzymesIBA 02/2012
1	BradykininIBA 02/2012
1	R 59949IBA 05/2011
1	TrehaloseIBA 10/2010
1	DisaccharidesIBA 10/2010
1	Interleukin-12 (IL 12)IBA 02/2010
1	Immunologic Factors (Immunomodulators)IBA 02/2010
1	Congo RedIBA 01/2010
1	Nerve Growth Factor (NGF)IBA 12/2009
1	BryostatinsIBA 06/2009
1	prostratinIBA 06/2009
1	Antineoplastic Agents (Antineoplastics)IBA 06/2009
1	Therapeutic UsesIBA 06/2009
1	superoxide-forming enzymeIBA 09/2008
1	LigandsIBA 04/2008
1	1-hexylindolactam-V10IBA 01/2008
1	UbiquitinIBA 12/2007
1	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2007
1	Protein Kinase C-epsilonIBA 09/2007

Therapy/Procedure

3	Therapeutics 01/2021 - 09/2006
1	Transplantation 12/2018
1	Mandibular Reconstruction 12/2018
1	Distraction Osteogenesis 12/2018
1	Biological Therapy 02/2010
1	Lasers (Laser) 04/2009